One of the most sought-after leading man gigs in Hollywood at the moment is definitely Doctor Strange. After the announcement that Scott Derrickson would direct the film, the search is on for a person who can convey the gravitas of Doctor Stephen Strange.
One of the names in contention for the role is Jared Leto. Having just won the Academy Award for Dallas Buyers Club, Leto seems like he'd be a pretty hot choice for the part. He comes with prestige, and talent, but he's not going to break the bank, and this will largely be a fresh face for the audience to embrace, since Leto isn't exactly a household name.